Serotonin Transporter Promoter Gain-of-Function Genotypes Are Linked to Obsessive-Compulsive Disorder

A functional serotonin transporter promoter polymorphism, HTTLPR, alters the risk of disease as well as brain morphometry and function. Here, we show that HTTLPR is functionally triallelic. The L(G) allele, which is the L allele with a common G substitution, creates a functional AP2 transcription-fa...

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Detalhes bibliográficos
Main Authors: Hu, Xian-Zhang, Lipsky, Robert H., Zhu, Guanshan, Akhtar, Longina A., Taubman, Julie, Greenberg, Benjamin D., Xu, Ke, Arnold, Paul D., Richter, Margaret A., Kennedy, James L., Murphy, Dennis L., Goldman, David
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474042/
https://ncbi.nlm.nih.gov/pubmed/16642437
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