microRNAs exhibit high frequency genomic alterations in human cancer

MicroRNAs (miRNAs) are endogenous noncoding RNAs, which negatively regulate gene expression. To determine genomewide miRNA DNA copy number abnormalities in cancer, 283 known human miRNA genes were analyzed by high-resolution array-based comparative genomic hybridization in 227 human ovarian cancer,...

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Detalhes bibliográficos
Main Authors: Zhang, Lin, Huang, Jia, Yang, Nuo, Greshock, Joel, Megraw, Molly S., Giannakakis, Antonis, Liang, Shun, Naylor, Tara L., Barchetti, Andrea, Ward, Michelle R., Yao, George, Medina, Angelica, O’Brien-Jenkins, Ann, Katsaros, Dionyssios, Hatzigeorgiou, Artemis, Gimotty, Phyllis A., Weber, Barbara L., Coukos, George
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474008/
https://ncbi.nlm.nih.gov/pubmed/16754881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508889103
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