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Structural and dynamic characteristics of a partially folded state of ubiquitin revealed by hydrogen exchange mass spectrometry

Structural and dynamic properties of a partially folded conformation (A-state) of ubiquitin are studied using amide hydrogen exchange in solution (HDX) and mass spectrometric detection. A clear distinction between the native state of the protein and the A-state can be made when HDX is carried out in...

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Bibliografske podrobnosti
Main Authors: Hoerner, Joshua K., Xiao, Hui, Kaltashov, Igor A.
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473987/
https://ncbi.nlm.nih.gov/pubmed/16101313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0509548
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