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Combinatorial library diversity: probability assessment of library populations.

A method is described for measuring the diversity of combinatorial oligonucleotide libraries that entails extrapolating the base composition of a co-synthesized model library (dNC, N = A, C, G, T) to that of a multibase library template. The base composition of dNC was measured by HPLC. The ability...

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Bibliografiska uppgifter
Huvudupphovsmän: Ward, B, Juehne, T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1998
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC147359/
https://ncbi.nlm.nih.gov/pubmed/9461443
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