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Variants in the GH-IGF axis confer susceptibilityto lung cancer

We conducted a large-scale genome-wide association study in UK Caucasians to identify susceptibility alleles for lung cancer, analyzing 1529 cases and 2707 controls. To increase the likelihood of identifying disease-causing alleles, we genotyped 1476 nonsynonymous single nucleotide polymorphisms (ns...

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Detalhes bibliográficos
Main Authors: Rudd, Matthew F., Webb, Emily L., Matakidou, Athena, Sellick, Gabrielle S., Williams, Richard D., Bridle, Helen, Eisen, Tim, Houlston, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473180/
https://ncbi.nlm.nih.gov/pubmed/16741161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5120106
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