Differential replication timing of X-linked genes measured by a novel method using single-nucleotide primer extension.
The ratio of two differentially replicating alleles is not constant during S phase. Using this fact, we have developed a method for determining allele-specific replication timing for alleles differing by at least a single base pair. Unsynchronized cells in tissue culture are first sorted into fracti...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9421536/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.2.684 |
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