Differential replication timing of X-linked genes measured by a novel method using single-nucleotide primer extension.

The ratio of two differentially replicating alleles is not constant during S phase. Using this fact, we have developed a method for determining allele-specific replication timing for alleles differing by at least a single base pair. Unsynchronized cells in tissue culture are first sorted into fracti...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Xiong, Z, Tsark, W, Singer-Sam, J, Riggs, A D
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1998
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9421536/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.2.684
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