A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys

Nonenzymatic glycosylation and cross-linking of proteins by glucose contributes to an age-associated increase in vascular and myocardial stiffness. Some recently sythesized thiazolium compounds selectively break these protein cross-links, reducing collagen stiffness. We investigated the effects of 3...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Vaitkevicius, Peter V., Lane, Mark, Spurgeon, Harold, Ingram, Donald K., Roth, George S., Egan, John J., Vasan, Sara, Wagle, Dilip R., Ulrich, Peter, Brines, Michael, Wuerth, Jean Paul, Cerami, Anthony, Lakatta, Edward G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.3.1171
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!