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Mutations in Influenza Virus M1 CCHH, the Putative Zinc Finger Motif, Cause Attenuation in Mice and Protect Mice against Lethal Influenza Virus Infection

Mutations in CCHH, the putative zinc finger motif, apparently do not play an important role in virus replication in MDCK cells in culture (E. K.-W. Hui, K. Ralston, A. K. Judd, and D. P. Nayak, J. Gen. Virol. 84:3105-3113, 2003). In this report, however, we demonstrate that the CCHH motif plays a cr...

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Bibliografische gegevens
Hoofdauteurs: Hui, Eric Ka-Wai, Smee, Donald F., Wong, Min-Hui, Nayak, Debi P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472591/
https://ncbi.nlm.nih.gov/pubmed/16731908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02729-05
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