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Endosomal Proteolysis by Cathepsins Is Necessary for Murine Coronavirus Mouse Hepatitis Virus Type 2 Spike-Mediated Entry

Most strains of murine coronavirus mouse hepatitis virus (MHV) express a cleavable spike glycoprotein that mediates viral entry and pH-independent cell-cell fusion. The MHV type 2 (MHV-2) strain of murine coronavirus differs from other strains in that it expresses an uncleaved spike and cannot induc...

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Autors principals: Qiu, Zhaozhu, Hingley, Susan T., Simmons, Graham, Yu, Christopher, Das Sarma, Jayasri, Bates, Paul, Weiss, Susan R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472567/
https://ncbi.nlm.nih.gov/pubmed/16731916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00442-06
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