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μ Opioid receptor A118G polymorphism in association with striatal opioid neuropeptide gene expression in heroin abusers

μ Opioid receptors are critical for heroin dependence, and A118G SNP of the μ opioid receptor gene (OPRM1) has been linked with heroin abuse. In our population of European Caucasians (n = 118), ≈90% of 118G allelic carriers were heroin users. Postmortem brain analyses showed the OPRM1 genotype assoc...

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Detalhes bibliográficos
Main Authors: Drakenberg, Katarina, Nikoshkov, Andrej, Horváth, Monika Cs, Fagergren, Pernilla, Gharibyan, Anna, Saarelainen, Kati, Rahman, Sadia, Nylander, Ingrid, Bakalkin, Georgy, Rajs, Jovan, Keller, Eva, Hurd, Yasmin L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472539/
https://ncbi.nlm.nih.gov/pubmed/16682632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600871103
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