Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator

Purkinje neurons (PNs), the central cells in cerebellar circuitry and function, constitute a vulnerable population in many human genetic, malignant, hypoxic, and toxic diseases. In the nervous (nr) mutant mouse, the majority of PNs die in the fourth to fifth postnatal weeks, but the responsible mole...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Jianxue, Ma, Yinghua, Teng, Yang D., Zheng, Kangni, Vartanian, Timothy K., Snyder, Evan Y., Sidman, Richard L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472533/
https://ncbi.nlm.nih.gov/pubmed/16682647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602440103
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