Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP

The Wingless pathway plays an essential role during synapse development. Recent studies at Drosophila glutamatergic synapses suggest that Wingless is secreted by motor neuron terminals and binds to postsynaptic Drosophila Frizzled-2 (DFz2) receptors. DFz2 is, in turn, endocytosed and transported to...

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Main Authors: Ataman, Bulent, Ashley, James, Gorczyca, David, Gorczyca, Michael, Mathew, Dennis, Wichmann, Carolin, Sigrist, Stephan J., Budnik, Vivian
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472532/
https://ncbi.nlm.nih.gov/pubmed/16682643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600387103
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