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Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP

The Wingless pathway plays an essential role during synapse development. Recent studies at Drosophila glutamatergic synapses suggest that Wingless is secreted by motor neuron terminals and binds to postsynaptic Drosophila Frizzled-2 (DFz2) receptors. DFz2 is, in turn, endocytosed and transported to...

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書誌詳細
主要な著者: Ataman, Bulent, Ashley, James, Gorczyca, David, Gorczyca, Michael, Mathew, Dennis, Wichmann, Carolin, Sigrist, Stephan J., Budnik, Vivian
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472532/
https://ncbi.nlm.nih.gov/pubmed/16682643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600387103
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