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Langerhans cells cross-present antigen derived from skin

Dendritic cells (DC) efficiently cross-present exogenous antigen on MHC class I molecules to CD8(+) T cells. However, little is known about cross-presentation by Langerhans cells (LC), the DCs of the epidermis. Therefore, we investigated this issue in detail. Isolated murine LCs were able to cross-p...

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Detalhes bibliográficos
Main Authors: Stoitzner, Patrizia, Tripp, Christoph H., Eberhart, Andreas, Price, Kylie M., Jung, Jae Y., Bursch, Laura, Ronchese, Franca, Romani, Nikolaus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472522/
https://ncbi.nlm.nih.gov/pubmed/16672373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509307103
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