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siRNA in human cells selectively localizes to target RNA sites

Recent observations of RNA interference (RNAi) in the nuclei of human cells raise key questions about the extent to which nuclear and cytoplasmic RNAi pathways are shared. By directly visualizing the localization of small interfering RNA (siRNA) in live human cells, we show here that siRNA either se...

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Detalhes bibliográficos
Main Authors: Berezhna, Svitlana Y., Supekova, Lubica, Supek, Frantisek, Schultz, Peter G., Deniz, Ashok A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472505/
https://ncbi.nlm.nih.gov/pubmed/16684885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600148103
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