Newcastle disease virus expressing H5 hemagglutinin gene protects chickens against Newcastle disease and avian influenza

Newcastle disease virus (NDV)-expressing avian influenza virus (AIV) hemagglutinin (HA) of subtype H5 was constructed by reverse genetics. A cloned full-length copy of the genome of the lentogenic NDV strain Clone 30 was used for insertion of the ORF encoding the HA of the highly pathogenic AIV isol...

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Hauptverfasser: Veits, Jutta, Wiesner, Dorothee, Fuchs, Walter, Hoffmann, Bernd, Granzow, Harald, Starick, Elke, Mundt, Egbert, Schirrmeier, Horst, Mebatsion, Teshome, Mettenleiter, Thomas C., Römer-Oberdörfer, Angela
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472452/
https://ncbi.nlm.nih.gov/pubmed/16717197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602461103
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