Chimeric newcastle disease virus protects chickens against avian influenza in the presence of maternally derived NDV immunity.

Newcastle disease virus (NDV), an avian paramyxovirus type 1, is a promising vector for expression of heterologous proteins from a variety of unrelated viruses including highly pathogenic avian influenza virus (HPAIV). However, pre-existing NDV antibodies may impair vector virus replication, resulti...

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Hlavní autoři: Constanze Steglich, Christian Grund, Kristina Ramp, Angele Breithaupt, Dirk Höper, Günther Keil, Jutta Veits, Mario Ziller, Harald Granzow, Thomas C Mettenleiter, Angela Römer-Oberdörfer
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2013-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3762792?pdf=render
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