Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells

Stem cells represent a unique population of cells with self-renewal capacity. Although they are important therapeutic targets, the genetic manipulation of tissue-specific stem cells has been limited, which complicates the study and practical application of these cells. Here, we demonstrate successfu...

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Bibliografiske detaljer
Main Authors: Kanatsu-Shinohara, Mito, Ikawa, Masahito, Takehashi, Masanori, Ogonuki, Narumi, Miki, Hiromi, Inoue, Kimiko, Kazuki, Yasuhiro, Lee, Jiyoung, Toyokuni, Shinya, Oshimura, Mitsuo, Ogura, Atsuo, Shinohara, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472422/
https://ncbi.nlm.nih.gov/pubmed/16679411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601139103
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