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Increased Susceptibility to Pulmonary Hypertension in Heterozygous BMPR2-Mutant Mice

BACKGROUND: Bone morphogenetic protein (BMP) receptor-II (BMPR2) heterozygous mutant (BMPR2+/−) mice have a similar genetic trait as certain patients with idiopathic pulmonary arterial hypertension (IPAH). To understand the role of the BMPR2 in the development of IPAH, we examined the phenotype of B...

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Main Authors: Song, Yanli, Jones, John E., Beppu, Hideyuki, Keaney, John F., Loscalzo, Joseph, Zhang, Ying-Yi
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472405/
https://ncbi.nlm.nih.gov/pubmed/16027259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.104.492488
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