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Two-stage mechanism for activation of the DNA replication checkpoint kinase Cds1 in fission yeast

The DNA replication checkpoint is a complex signal transduction pathway, present in all eukaryotic cells, that functions to maintain genomic integrity and cell viability when DNA replication is perturbed. In Schizosaccharomyces pombe the major effector of the replication checkpoint is the protein ki...

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Autors principals: Xu, Yong, Davenport, Matthew, Kelly, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472306/
https://ncbi.nlm.nih.gov/pubmed/16618806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1406706
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