OAS and PKR are not Required for the Anti-viral Effect of Ad:IFN-γ Against Acute HSV-1 in Primary Trigeminal Ganglia Cultures

Three interferon-gamma (IFNG) induced anti-viral pathways have been reported. Involved anti-viral proteins include: Mx, RNaseL/2'-5'-OAS, and PKR. Involvement of OAS and PKR in IFNG-induced anti-HSV-1 pathways has not been previously reported, but IFNG induces OAS and PKR when other viruse...

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Autores principales: Austin, Bobbie Ann, Halford, William, Silverman, Robert H., Williams, Bryan R. G., Carr, Daniel J. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472294/
https://ncbi.nlm.nih.gov/pubmed/16704298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2006.26.220
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