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Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains

The M channels, important regulators of neuronal excitability, are voltage-gated potassium channels composed of KCNQ2–5 subunits. Mutations in KCNQ2 and KCNQ3 cause benign familial neonatal convulsions (BFNC), dominantly inherited epilepsy and myokymia. Crucial for their functions in controlling neu...

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Detalhes bibliográficos
Main Authors: Chung, Hee Jung, Jan, Yuh Nung, Jan, Lily Y.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472242/
https://ncbi.nlm.nih.gov/pubmed/16735477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603376103
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