Poly(I)-Poly(C(12)U) but Not Ribavirin Prevents Death in a Hamster Model of Nipah Virus Infection

Clinical nonrandomized trials demonstrate some efficacy for ribavirin in the treatment of patients with severe Nipah virus-induced encephalitis. We report here that EICAR, the 5-ethynyl analogue of ribavirin, and the OMP-decarboxylase inhibitors 6-aza-uridine and pyrazofurin have strong antiviral ac...

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Main Authors: Georges-Courbot, M. C., Contamin, H., Faure, C., Loth, P., Baize, S., Leyssen, P., Neyts, J., Deubel, V.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2006
主題:
Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472238/
https://ncbi.nlm.nih.gov/pubmed/16641448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1768-1772.2006
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