Intrapulmonary Penetration of Voriconazole in Patients Receiving an Oral Prophylactic Regimen

Voriconazole penetrated well into the pulmonary epithelial lining fluid (ELF) in lung transplant patients receiving oral prophylaxis. The ELF concentrations exceeded those of the plasma, with an average ELF-to-plasma ratio of 11 (±8). A strong association between plasma and ELF concentrations (r(2)...

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Bibliographische Detailangaben
Hauptverfasser: Capitano, Blair, Potoski, Brian A., Husain, Shahid, Zhang, Shimin, Paterson, David L., Studer, Sean M., McCurry, Kenneth R., Venkataramanan, Raman
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472209/
https://ncbi.nlm.nih.gov/pubmed/16641467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1878-1880.2006
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