Acetylation of the Latency-Associated Nuclear Antigen Regulates Repression of Kaposi's Sarcoma-Associated Herpesvirus Lytic Transcription

Reactivation of the Kaposi's sarcoma-associated herpesvirus (KSHV) lytic cycle can be initiated by transcription activation of the ORF50 immediate early gene (Rta). We show that ORF50 transcription is actively repressed by the KSHV latency-associated nuclear antigen (LANA) during latency. Deple...

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Hlavní autoři: Lu, Fang, Day, Latasha, Gao, S.-J., Lieberman, Paul M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472144/
https://ncbi.nlm.nih.gov/pubmed/16699007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02541-05
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