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A Short Isoform of Human Cytomegalovirus US3 Functions as a Dominant Negative Inhibitor of the Full-Length Form

Human cytomegalovirus encodes four unique short (US) region proteins, each of which is independently sufficient for causing the down-regulation of major histocompatibility complex (MHC) class I molecules on the cell surface. This down-regulation enables infected cells to evade recognition by cytotox...

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Hlavní autoři: Shin, Jinwook, Park, Boyoun, Lee, Sungwook, Kim, Youngkyun, Biegalke, Bonita J., Kang, Seongman, Ahn, Kwangseog
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472136/
https://ncbi.nlm.nih.gov/pubmed/16699020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02397-05
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