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Human Papillomavirus Type 16 E6 Activates NF-κB, Induces cIAP-2 Expression, and Protects against Apoptosis in a PDZ Binding Motif-Dependent Manner

Infection with human papillomavirus (HPV) is a critical factor in the pathogenesis of most cervical cancers and some aerodigestive cancers. The HPV E6 oncoprotein from high-risk HPV types contributes to the immortalization and transformation of cells by multiple mechanisms, including degradation of...

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Detalhes bibliográficos
Main Authors: James, Michael A., Lee, John H., Klingelhutz, Aloysius J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472131/
https://ncbi.nlm.nih.gov/pubmed/16699010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01942-05
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