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A gene trap approach to isolate mammalian genes involved in the cellular response to genotoxic stress.

Treatment of cells with DNA damaging agents leads to induction of a variety of genes involved in different cellular processes. We have applied a lacZ-based gene trap strategy to search for new mammalian genes induced by genotoxic stress. A population of 32 x 10(3) neo r clones stably transfected wit...

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Autors principals: Menichini, P, Viaggi, S, Gallerani, E, Fronza, G, Ottaggio, L, Comes, A, Ellwart, J W, Abbondandolo, A
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC147125/
https://ncbi.nlm.nih.gov/pubmed/9365260
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