Reprogramming of telomerase activity and rebuilding of telomere length in cloned cattle

Nuclear reprogramming requires the removal of epigenetic modifications imposed on the chromatin during cellular differentiation and division. The mammalian oocyte can reverse these alterations to a state of totipotency, allowing the production of viable cloned offspring from somatic cell nuclei. To...

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Bibliografiske detaljer
Main Authors: Betts, Dean H., Bordignon, Vilceu, Hill, Jonathan R., Winger, Quinton, Westhusin, Mark E., Smith, Lawrence C., King, W. Allan
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14711/
https://ncbi.nlm.nih.gov/pubmed/11158597
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