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Reprogramming of telomerase activity and rebuilding of telomere length in cloned cattle

Nuclear reprogramming requires the removal of epigenetic modifications imposed on the chromatin during cellular differentiation and division. The mammalian oocyte can reverse these alterations to a state of totipotency, allowing the production of viable cloned offspring from somatic cell nuclei. To...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Betts, Dean H., Bordignon, Vilceu, Hill, Jonathan R., Winger, Quinton, Westhusin, Mark E., Smith, Lawrence C., King, W. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.031559298
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