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Functional dissection of the gamma-tubulin complex by suppressor analysis of gtb1 and alp4 mutations in Schizosaccharomyces pombe.

In fission yeast, gamma-tubulin (encoded by the gtb1+ gene), Alp4 (Spc97/GCP2), and Alp6 (Spc98/GCP3) are essential components of the gamma-tubulin complex. We isolated gtb1 mutants as allele-specific suppressors of temperature-sensitive alp4 mutations. Mutation sites in gtb1 mutants and in several...

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Autores principales: Tange, Yoshie, Fujita, Akiko, Toda, Takashi, Niwa, Osami
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470944/
https://ncbi.nlm.nih.gov/pubmed/15280226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.027946
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