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A quantitative trait locus mixture model that avoids spurious LOD score peaks.
In standard interval mapping of quantitative trait loci (QTL), the QTL effect is described by a normal mixture model. At any given location in the genome, the evidence of a putative QTL is measured by the likelihood ratio of the mixture model compared to a single normal distribution (the LOD score)....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1470903/ https://ncbi.nlm.nih.gov/pubmed/15238544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.025437 |
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