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Smoothing of the bivariate LOD score for non-normal quantitative traits
Variance component analysis provides an efficient method for performing linkage analysis for quantitative traits. However, type I error of variance components-based likelihood ratio testing may be affected when phenotypic data are non-normally distributed (especially with high values of kurtosis). T...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866827/ https://ncbi.nlm.nih.gov/pubmed/16451568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S111 |
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