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Detecting selection in noncoding regions of nucleotide sequences.
We present a maximum-likelihood method for examining the selection pressure and detecting positive selection in noncoding regions using multiple aligned DNA sequences. The rate of substitution in noncoding regions relative to the rate of synonymous substitution in coding regions is modeled by a para...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1470900/ https://ncbi.nlm.nih.gov/pubmed/15238543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.102.010959 |
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