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Accuracy and Power of Statistical Methods for Detecting Adaptive Evolution in Protein Coding Sequences and for Identifying Positively Selected Sites

The parsimony method of Suzuki and Gojobori (1999) and the maximum likelihood method developed from the work of Nielsen and Yang (1998) are two widely used methods for detecting positive selection in homologous protein coding sequences. Both methods consider an excess of nonsynonymous (replacement)...

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Detalhes bibliográficos
Main Authors: Wong, Wendy S. W., Yang, Ziheng, Goldman, Nick, Nielsen, Rasmus
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448811/
https://ncbi.nlm.nih.gov/pubmed/15514074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.031153
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