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Accuracy and Power of Statistical Methods for Detecting Adaptive Evolution in Protein Coding Sequences and for Identifying Positively Selected Sites

The parsimony method of Suzuki and Gojobori (1999) and the maximum likelihood method developed from the work of Nielsen and Yang (1998) are two widely used methods for detecting positive selection in homologous protein coding sequences. Both methods consider an excess of nonsynonymous (replacement)...

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Sonraí Bibleagrafaíochta
Main Authors: Wong, Wendy S. W., Yang, Ziheng, Goldman, Nick, Nielsen, Rasmus
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2004
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448811/
https://ncbi.nlm.nih.gov/pubmed/15514074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.031153
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