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Regulation of the Drosophila epidermal growth factor-ligand vein is mediated by multiple domains.
Vein (Vn), a ligand for the Drosophila epidermal growth factor receptor (Egfr), has a complex structure including a PEST, Ig, and EGF domain. We analyzed the structure-function relationships of Vn by assaying deletion mutants. The results show that each conserved domain influences Vn activity. A PES...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1470887/ https://ncbi.nlm.nih.gov/pubmed/15238521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.019588 |
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