Opening of the extraordinarily stable mini-hairpin d(GCGAAGC).
For the purposes of the antisense strategy oligodeoxyribonucleotides can be protected against serum and cell nuclease digestion by tagging at their 3'-end with a sequence naturally forming a very stable hairpin, d(GCGAAGC). This nuclease-resistant hairpin is also known for its high thermostability....
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147075/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9358172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.22.4608 |
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