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Opening of the extraordinarily stable mini-hairpin d(GCGAAGC).

For the purposes of the antisense strategy oligodeoxyribonucleotides can be protected against serum and cell nuclease digestion by tagging at their 3'-end with a sequence naturally forming a very stable hairpin, d(GCGAAGC). This nuclease-resistant hairpin is also known for its high thermostability....

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Udgivet i:Nucleic Acids Res
Principais autores: Jollès, B, Réfrégiers, M, Laigle, A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9358172/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.22.4608
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