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Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants.

Here we examine the roles of budding-yeast checkpoint proteins in regulating degradation of dsDNA to ssDNA at unprotected telomeres (in Cdc13 telomere-binding protein defective strains). We find that Rad17, Mec3, as well as Rad24, members of the putative checkpoint clamp loader (Rad24) and sliding c...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jia, Xindan, Weinert, Ted, Lydall, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470748/
https://ncbi.nlm.nih.gov/pubmed/15020465
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