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sel-7, a positive regulator of lin-12 activity, encodes a novel nuclear protein in Caenorhabditis elegans.

Suppressor genetics in C. elegans has identified key components of the LIN-12/Notch signaling pathway. Here, we describe a genetic and molecular characterization of the suppressor gene sel-7. We show that reducing or eliminating sel-7 activity suppresses the effects of constitutive lin-12 activity,...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Jiabin, Li, Xiajun, Greenwald, Iva
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2004
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470699/
https://ncbi.nlm.nih.gov/pubmed/15020414
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