Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice.

In the course of a large-scale program of ENU mutagenesis, we isolated a dominant mutation, called Velvet. The mutation was found to be uniformly lethal to homozygotes, which do not survive E13.5. Mice heterozygous for the Velvet mutation are born with eyelids open and demonstrate a wavy coat and cu...

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Detalhes bibliográficos
Main Authors: Du, Xin, Tabeta, Koichi, Hoebe, Kasper, Liu, Haiquan, Mann, Navjiwan, Mudd, Suzanne, Crozat, Karine, Sovath, Sosathya, Gong, Xiaohua, Beutler, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470694/
https://ncbi.nlm.nih.gov/pubmed/15020428
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