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Functional significance of the TATA element major groove in transcription initiation by RNA polymerase II.

The binding of TFIID to the TATA element initiates assembly of a preinitiation complex and thus represents one of the most important steps for transcriptional regulation. The fact that the TATA binding protein (TBP), a subunit of TFIID, exclusively contacts the minor groove of the TATA element led u...

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Dettagli Bibliografici
Autori principali: Lee, D K, Wang, K C, Roeder, R G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC147030/
https://ncbi.nlm.nih.gov/pubmed/9336466
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