Functional significance of the TATA element major groove in transcription initiation by RNA polymerase II.

The binding of TFIID to the TATA element initiates assembly of a preinitiation complex and thus represents one of the most important steps for transcriptional regulation. The fact that the TATA binding protein (TBP), a subunit of TFIID, exclusively contacts the minor groove of the TATA element led u...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Lee, D K, Wang, K C, Roeder, R G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147030/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9336466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.21.4338
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