A proposed approach to study the toxicology of complex mixtures of petroleum products: the integrated use of QSAR, lumping analysis and PBPK/PD modeling.

Mixture toxicity is a topic that has become a matter of concern during the last two decades. One of the major problems with assessing the toxicity of mixtures and the associated human and environmental risk is the large number of possible mixtures, as well as the fact that the actual mixture effect...

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Main Authors: Verhaar, H J, Morroni, J R, Reardon, K F, Hays, S M, Gaver, D P, Carpenter, R L, Yang, R S
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470291/
https://ncbi.nlm.nih.gov/pubmed/9114286
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