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A proposed approach to study the toxicology of complex mixtures of petroleum products: the integrated use of QSAR, lumping analysis and PBPK/PD modeling.

Mixture toxicity is a topic that has become a matter of concern during the last two decades. One of the major problems with assessing the toxicity of mixtures and the associated human and environmental risk is the large number of possible mixtures, as well as the fact that the actual mixture effect...

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Detalhes bibliográficos
Main Authors: Verhaar, H J, Morroni, J R, Reardon, K F, Hays, S M, Gaver, D P, Carpenter, R L, Yang, R S
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470291/
https://ncbi.nlm.nih.gov/pubmed/9114286
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