Transcriptional activation of the human rod cGMP-phosphodiesterase beta-subunit gene is mediated by an upstream AP-1 element.

During photoactivation retinal cGMP-phosphodiesterase (PDE) mediates signal transduction in the photoreceptor outer segments. Mutations in the beta-subunit gene of rod-specific PDE (beta-PDE) have been associated with inherited retinal degeneration in a number of species, including human. Here we ha...

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Bibliografski detalji
Glavni autori: Di Polo, A, Lerner, L E, Farber, D B
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC146967/
https://ncbi.nlm.nih.gov/pubmed/9380509
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