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Monitoring populations for DNA repair deficiency and for cancer susceptibility.

The induction of a mutator phenotype has been hypothesized to cause the accumulation of multiple mutations in the development of cancer. Recent evidence suggests that the mutator phenotype is associated with DNA repair deficiencies. We have been using a challenge assay to study exposed populations t...

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Detalhes bibliográficos
Main Authors: Au, W W, Wilkinson, G S, Tyring, S K, Legator, M S, el Zein, R, Hallberg, L, Heo, M Y
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1469634/
https://ncbi.nlm.nih.gov/pubmed/8781386
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