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Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

Smad proteins are key intracellular signaling effectors for the transforming growth factor-β superfamily of peptide growth factors. Following receptor-induced activation, Smads move into the nucleus to activate transcription of a select set of target genes. The activity of Smad proteins must be tigh...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Ying, Chang, Chenbei, Gehling, Daniel J., Hemmati-Brivanlou, Ali, Derynck, Rik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14694/
https://ncbi.nlm.nih.gov/pubmed/11158580
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