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The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities.

EP is a DNA element found in regulatory regions of viral and cellular genes. While being a key functional element in viral enhancers, EP has no intrinsic enhancer activity but can stimulate or silence transcription in a context-dependent manner. The EP element is bound by RFX1, which belongs to a no...

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Detalhes bibliográficos
Main Authors: Katan, Y, Agami, R, Shaul, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146931/
https://ncbi.nlm.nih.gov/pubmed/9278482
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